Blood transfusion is associated with increased resource utilisation, morbidity, and mortality in cardiac surgery

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Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery

Background—Red blood cell transfusion can both benefit and harm. To inform decisions about transfusion, we aimed to quantify associations of transfusion with clinical outcomes and cost in patients having cardiac surgery. Methods and Results—Clinical, hematology, and blood transfusion databases were linked with the UK population register. Additional hematocrit information was obtained from inten...

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Transfusion of leukocyte-depleted RBCs is independently associated with increased morbidity after pediatric cardiac surgery.

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Low Vitamin D Concentration Is Not Associated with Increased Mortality and Morbidity after Cardiac Surgery

OBJECTIVE To determine the effect of vitamin D on postoperative outcomes in cardiac surgical patients. DESIGN Retrospective study. SETTING Single institution-teaching hospital. PARTICIPANTS Adult cardiac surgical patients with perioperative 25-hydroxyvitamin D measurements. INTERVENTIONS None. We gathered information from the Cardiac Anesthesiology Registry that was obtained at the time...

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Transfusion of 1 and 2 units of red blood cells is associated with increased morbidity and mortality.

BACKGROUND This study examined the relationship between transfusion of 1 or 2 units of red blood cells (RBCs) and the risk of morbidity and mortality after isolated on-pump coronary artery bypass grafting (CABG). METHODS A total of 22,785 consecutive patients underwent isolated on-pump CABG between January 1, 2008, and December 31, 2011 in Michigan. We excluded 5,950 patients who received thr...

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Increased risk of infection and mortality in women after cardiac surgery related to allogeneic blood transfusion.

BACKGROUND Infection and mortality rates are greater in women than in men after cardiac surgery. This study was conducted to assess whether allogeneic blood transfusion could partially account for this gender difference, as transfusion has been associated with immunomodulation. METHODS A cohort study was conducted in 380 patients at the University of Rochester Medical Center. Subjects were ad...

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ژورنال

عنوان ژورنال: Annals of Cardiac Anaesthesia

سال: 2008

ISSN: 0971-9784

DOI: 10.4103/0971-9784.41591